Dironet Spot-On drops on the withers for dogs against ecto- and endoparasites 4 pipettes

In the article you will learn what kind of drug Dironet is for cats, its purpose, rules of use, nature of action, composition, side effects, storage rules. Essentially, Dironet is an antiparasitic drug that is intended for the treatment of adult cats and small kittens. The development of its unique formula was carried out by the Agrovetzashchita enterprise. It effectively copes with helminths (worms) that parasitize the body of domestic animals. Prescribed when infestation by endoparasites of varying severity is detected.

Thanks to the substances included in its composition, it helps not only in the initial stages of parasite infection, but also in extremely advanced cases.

Dironet is a universal medication against worms in cats and dogs. The manufacturer is domestic. A significant advantage of the medicine is its availability - it is sold in any veterinary pharmacy without a prescription. But before you settle on it, you should read the instructions for use and other important nuances.

Instructions for use

The medicine Dironet for cats is available in several dosage forms in the form of suspensions, tablets, drops. Each of them has its own instructions for use.

1. The suspension must be given to the pet once a day before feeding it in the morning. As a rule, cats use the drug without problems, since the manufacturer gives it the smell and taste of salmon.
2. The tablets should only be used to treat adult pets. Medicines must be given either forcibly or mixed with wet food. Six ways to give a cat a pill.
3. Spot-on drops are packaged in special tubes that are quite easy to use. They are used to get rid of ear mites, common mites, fleas and lice. In addition, drops are used to cure diseases such as notoendrosis and sarcoptic mange. To prevent your cat from licking the product, it is dripped onto the skin located in the withers area.

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Anthelmintic drug

Suspension for kittens

Dironet for adult cats in the form of a suspension is a viscous substance of yellow-gray color. It is packaged in 10 ml polymer bottles. The liquid may separate into layers, which disappear when vigorously agitated. The kit includes a special dispenser syringe.

For kittens, the manufacturer has provided a separate medicine of this brand - Diorent Junior.

Its advantages:

• unlike other antiparasitic drugs, it does not suppress the immune system;
• after the destruction of helminths, promotes rapid regeneration of damaged gastrointestinal tissues;
• the drug acts only in the intestines, so it is not contraindicated if the animal has liver or kidney diseases.

Dironet Junior Suspension
This drug is indicated for babies over 20 weeks of age for the prevention and treatment of the following diseases:

• toxocariasis;
• toxascariasis;
• dipylidia;
• uncinarium;
• dirofilariasis;
• trichocephalosis:
• hookworms;
• trichocephalosis.

As an antiparasitic treatment, as well as to get rid of microfilariae, the suspension should be given to the cat once a day in the morning, before feeding, or mixed into food.

As an antiparasitic treatment, as well as to get rid of microfilariae, the suspension should be given to the cat once a day in the morning, before feeding, or mixed into food. Usually the pet willingly consumes it because the medicine smells like fish. If the animal refuses, the suspension should be forcibly administered using a dropper pipette. Beforehand, shake the medicinal liquid well until smooth.

To prevent infection with worms, it is enough to use once a quarter, once a quarter, as well as before scheduled vaccinations (about a week in advance). For microfilariaemia in animals infected with parasites, one therapeutic dose is given monthly.

No special preparation is required before deworming with Diorent, such as diet or body cleansing. If you miss another dose of the drug, you can resume taking it at any time. Only this can reduce its effectiveness, so you should not delay treatment for long.

Purpose

Intestinal parasite infection is one of the most common diseases in pets. Dironet is an effective drug that is active against round and tape parasites, including:

• toxocara;
• uncinaria;
• hookworms;
• Echinococcus;
• taeniaids;
• tapeworm, which causes diphyllobothriasis, and other parasites.

The most common parasites in dogs are roundworms (up to 30% of animals are infected with them, and in puppies this figure reaches 60-70%). Living in the intestines of an animal, they may not show noticeable signs, however, with a large accumulation of parasites, the following symptoms may be present:

• bloating;
• vomit;
• diarrhea;
• respiratory signs – cough, pneumonia.

Hookworms

- Parasitic in the intestines of dogs, they feed on blood. This can cause serious blood loss, resulting in weakness, weight loss, and exhaustion. In puppies and weakened animals, prolonged blood loss can be fatal.

Whipworms

- another type of intestinal parasite that may not show its presence for a long time. Severe infestation is accompanied by bloody diarrhea, and if left untreated can lead to the death of the pet.

Statistics show that 60-80% of puppies become infected with helminths in utero. Adult animals can become infected by eating raw meat. Worm eggs are very tenacious and remain viable in the soil for up to 1-2 years. Regular preventive treatment of pets will reduce the risk of infection with parasites, many of which are dangerous to humans.

Helminthiasis is accompanied by characteristic symptoms, including vomiting, diarrhea, weakness, weight loss, cough and others. However, in many cases, the invasion is asymptomatic, while the parasites not only consume the nutrients necessary for the body, but damage tissues, internal organs, the nervous system, and cause intoxication of the body with the products of their vital activity.

Dironet

– one of the few antiparasitic drugs that are effective against heartworms. Heartworm disease is caused by parasites carried by mosquitoes. Cases of the disease have been increasingly recorded in different regions of Russia in recent years. The problem is acute in the Rostov region, where the disease has reached epidemic proportions; cases of dirofilariasis are often recorded in the south of the country and the Far East. People also get sick from it.

Dirofilaria (heartworms) cause in the pulmonary arteries of an animal:

• violation of the integrity of blood vessels;
• inflammation;
• pulmonary hypertension;
• fibrosis.

Release form

Types of Dironet
Available in several interpretations:

• Suspension. The liquid is a thick, dirty yellow color, poured into polymer bottles. The kit includes a dosing syringe.
• Pills. Packed in blisters of 200 capsules. The medicine is labeled The composition is similar to suspensions for adult cats, but the concentration of active ingredients is an order of magnitude higher. This makes it difficult to accurately calculate the dosage, so the tablet version is more often used for dogs.
• Spot-on solution. Drops for external use. They differ from the previous two types of medicine in their ability to destroy not only helminths, but also lice eaters, fleas and other parasites on domestic animals. The drug is available for adults (1 ml each) and for kittens (0.5 ml each). Sold in special tubes-pipettes (there are 3 of them in a box).

Contraindications.

Increased individual sensitivity of the animal to the components of the drug.

"Dironet spot-on" is prohibited for use by puppies and kittens under 2 months of age, pregnant, lactating animals, patients with infectious diseases and convalescent animals.

If it is necessary to use the drug for Collie, Bobtail and Sheltie puppies, due to the increased sensitivity of dogs of these breeds to ivermectin, treatment should be carried out under the supervision of the attending veterinarian.

Chemical composition

The chemical composition of all three varieties is almost identical. Active components:

• Pyrantel pamoate is a substance that inhibits the vital activity of tapeworms and roundworms in the animal’s body. It begins to act a few hours after ingestion, with the effect remaining for a long period. Due to this, the parasites are completely destroyed.
• Praziquantel - upon contact with parasitic infestations, it disables their metabolism and paralyzes. The substance works throughout the day until the pests die.
• Ivermectin is a substance that instantly enters the bloodstream through the cat's epidermis. As a result, pests (fleas, ticks) absorb the modified structure and soon die.

You cannot combine Dironet with other antiparasitic medications. Otherwise, an overdose is possible.

Dosage of medications

An anthelmintic drug is prescribed for use in appropriate dosages, depending on a number of factors: dosage form, concentration of active substances in the composition. Therefore, it is important to carefully read the instructions first.

The minimum allowable dose of the drug for mature cats is 0.2 ml per kilogram of animal weight, for kittens – 0.1 ml.

For tablets

Dironet tablets are rarely given to kittens, only to adult cats
Dironet tablets are rarely given to kittens, only to adult cats

If the choice is in the form of tablets, the dose is determined at the rate of 1 pill per 10 kilos of the total weight of the animal. The medicine is placed on the root of the tongue to make it easier for the animal to swallow, or it is pre-crushed and added to food. Tablet medicine is not recommended for children, since it is difficult to calculate the exact amount

Suspension dosage

The dosage depends on the weight of the cat: 1 ml of product is required per 1 kg. This applies to both adult cats and babies. If the kitten's weight is less than 500 grams, measure out 0.5 ml of the suspension and dissolve it in 0.3 ml of water that has cooled after boiling.

Order of application of the drop

Instructions Before applying the solution to the animal’s body, heat it to room temperature, shake the pipette tube well and cut off the tip with a sharp instrument. Then you need to carefully spread the fur in the area of ​​the shoulder blades (behind the ears or on the neck) and drop liquid onto the exposed area. These are the most optimal treatment areas that the cat will not be able to lick.

It is important to ensure that the epidermis does not have any damage and is dry. After the procedure, make sure that the cat does not come into contact with water for at least 3-4 days.

Recommendations for applying drops:

In case of overdose, the following symptoms of poisoning in the animal may occur:

• shaking of limbs;
• prostration;
• increased salivation.

Then you need to seek help from a doctor. But if you follow the regimen and dosages prescribed in the instructions, side effects usually do not occur.

Precautionary measures

When working with medicine, you must follow safety precautions and personal hygiene rules. Namely:

• before and after the procedure, wash your hands thoroughly with soap;
• while processing an animal, a person must not eat, drink, or smoke;
• It is unacceptable to touch the place of application of the drug with your hands and allow children near the cat for 2 days.

Dironet drops are applied to the animal’s withers

If the medication gets on the eye mucosa, rinse immediately with clean water. If the drug accidentally gets inside the body, do not delay contacting a doctor.

An empty medicine bottle should be disposed of immediately.

general description

The anthelmintic is sold in veterinary pharmacies in the form of tablets, suspension or solution for external use. Tablets are most effective against worms. The combination of three active components - praziquantel, pyrantel pamoate and ivermectin - has a long-lasting effect and is harmful to roundworms and tapeworms at any stage of their development. Dironet spot-on drops have a slightly different composition - they include two active components (ivermectin and praziquantel) and are used to combat ectoparasites, including carriers of dirofilariasis.

Operating principle

Suspension with tablets and drops operate according to different principles:

• the active substances of the suspension and tablets, after entering the gastrointestinal tract, begin to be quickly absorbed, after about 4 hours their concentration reaches its maximum value; nerve impulses begin to be transmitted with malfunctions, the permeability of intestinal cell membranes increases, as a result of which the parasites die;
• After applying drops to the skin in the withers area, the active components of the drug penetrate into the hair follicles and sebaceous glands. Reliable protection against ectoparasites is created (in addition, some substances penetrate into the blood, which helps destroy worms in the body).

The structure of a cat's skin

How to give to a dog

The product should be given to your pet strictly according to the instructions. It is unacceptable to independently increase or decrease the dosage or change the interval between uses. Otherwise, the therapy may not be effective and there is a risk of harm to the dog.

Do I need to prepare my pet?

No preliminary preparation is required before using the product. The medicine is given to the animal before morning feeding or mixed with food.

When using drops, you must avoid contact of the animal with water for four days after the procedure. In the next 24 hours, you should protect your pet from contact with children and other animals.

Do not let him lick the fur to avoid getting the substance inside.

For prevention purposes

When using the drug to prevent helminth damage, the drug is given to the pet every three months.

When preventing dirofilariasis, the medication is used once in early spring, and until October - monthly.

During therapy

When treating animals, the drug is given once. Two weeks later, the medication is taken again. In the future, an interval of about a month is maintained.

Compound

The active substances of the antiparasitic medicine are three main ingredients:

1. Pyrantel causes paralysis and subsequent death of the worms; due to long-term elimination from the cat’s body, it protects the animal’s gastrointestinal tract for a long time;
2. Ivermectin helps block neural impulses of helminths, which leads to their rapid death (also effectively destroys fleas, ticks, lice);
3. Praziquantel increases the permeability of cell membranes and disrupts the functioning of the nervous system of pests.

At the doctor

Dironet for cats and dogs

The anthelmintic Dironet for dogs is a deworming drug. The main active ingredients it contains are: pyrantel pamoate, praziquantel and ivermectin.

Dironet is a broad-spectrum anthelmintic. It actively affects round and tape helminths in all phases of their development, and also has a detrimental effect on microfilariae and thereby prevents dirofilariasis in dogs.

Principle of action After the dog swallows the drug, its active components are well absorbed in the stomach and intestines and penetrate into the tissues and organs of the animal. Ivermectin, which is part of the drug, affects the nerve and muscle cells of the parasite. The maximum concentration of the substance in the blood plasma is observed already 9 hours after entering the body. Pyrantel pamoate blocks neuromuscular transmission, which leads to paralysis and death of the parasite. The maximum concentration of the drug in the blood plasma occurs within 2-4 hours. In terms of the degree of impact on the body, Dironet is a low-hazard substance and is well tolerated by dogs in recommended doses.

Instructions for use of Dironet for dogs: dosage and contraindications It is prescribed for the prevention and treatment of cestodiasis and nematodes of the gastrointestinal tract, as well as for the prevention of dirofilariasis. For cestodiases and nematodes of the gastrointestinal tract, the drug is given once in the morning feeding at the rate of 1 tablet per 10 kg of dog weight.

Instructions for using Dironet for dogs

Before deworming, the use of laxatives and a special diet is not required. For prevention purposes, the drug should be given quarterly. In order to prevent dirofilariasis, the drug is used in the spring-summer-autumn period: before the start of mosquito summer once (March-April), then monthly until October.

When using Dironet according to the instructions, no complications or side effects are observed. If the dog's individual sensitivity is increased and allergic reactions occur, stop using the tablets.

The cost of the drug is about 30-35 rubles per tablet or 120 rubles for a blister with six tablets.

Reviews of Dironet for dogs.

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Instructions for use of the complex antiparasitic drug Dironet spot-on for cats

COMPOSITION AND RELEASE FORM Dironet spot-on contains ivermectin and praziquantel as active ingredients, as well as auxiliary components. In appearance it is a transparent solution of light yellow color with a weak specific odor. The drug is packaged in polymer dropper pipettes of 1 ml, which are packed in 3 pieces in cardboard boxes.

PHARMACOLOGICAL PROPERTIES Dironet spot-on is highly effective against a number of dangerous and widespread parasites in cats, such as roundworms and tapeworms: Toxascaris leonina, Toxocara mystax, Uncinaria stenocephala, Ancylostoma spp., Trichuris vulpis, Echinococcus granulosus, Echinococcus multilocularis, Multiceps multiceps, Mesocestoides lineatus, Diphyllobothrium latum, Dipylidium caninum, Taenia spp.; insects: Linognathus setosus, Trichodectes canis, Ctenocephalides felis; Sarcoptoid mites: Sarcoptes cati, Notoedres cati, Otodectes cynotis. The mechanism of action of ivermectin is to change the magnitude of the current of chlorine ions through the membranes of the neuromuscular cells of the parasite. The main targets are glutamate-sensitive chloride channels, as well as GABA receptors. A change in the current of chlorine ions disrupts the conduction of nerve impulses, which leads to paralysis and death of the parasite. The mechanism of action of praziquantel is based on disruption of glucose transport and microtubular function of cestodes, inhibition of fumarate reductase activity and ATP synthesis, increased permeability of cell membranes to calcium ions, which leads to disruption of neuromuscular innervation, paralysis and death of the parasite. Dironet spot-on, in terms of the degree of impact on the body of warm-blooded animals, is classified as a moderately hazardous substance and in recommended doses does not have a locally irritating, resorptive-toxic or sensitizing effect.

INDICATIONS Prevention of infestation of cats with sarcoptic mites. Prevention and treatment of cestodiases, nematodes and entomoses in cats.

DOSES AND METHOD OF APPLICATION Dironet spot-on is applied only to dry, intact skin of the animal in the doses indicated in the table:

Cat weight, kg Number of pipettes per animal, pcs. 2 − 5 1 more than 5 2

Before use, break off (or cut off) the tip of the pipette and then, spreading the animal’s fur, apply the drug at several points that are inaccessible for licking (at the base of the skull, between the shoulder blades, along the back). If an animal is affected by insects (fleas, lice and lice), the treatment is carried out once. For preventive purposes, the procedure should be carried out no more than once a month; to prevent re-infestation, it is recommended to treat the animal’s housing and bedding with an insecticidal-acaricidal spray in accordance with the instructions for use. To prevent sarcoptic mange and notoedrosis, Bars spot-on is applied 2–4 times with an interval of 10–14 days. For otodectosis (ear scabies), the treatment is carried out once, if necessary again after 5-10 days in combination with hygienic cleaning of the auricle and external auditory canal from dried crusts of exudate and scabs. In advanced cases of otodectosis, complicated by otitis, antibacterial and anti-inflammatory drugs are prescribed. For nematodes and cestodes for therapeutic purposes, the drug is applied once. The maximum therapeutic effect is observed 4–5 days after application. For preventive purposes, deworming is carried out once a quarter.

SIDE EFFECTS In rare cases, with increased individual sensitivity of the animal to the components of the drug and an overdose, muscle tremors, vomiting, excessive salivation and lacrimation, itching, irritation and redness of the skin may be observed. If these signs or other manifestations of intolerance appear, the drug should be immediately washed off with soap and water or shampoo.

CONTRAINDICATIONS Individual hypersensitivity to the components of the drug. Pregnant and lactating cats, as well as animals with infectious diseases and convalescent animals cannot be treated. The drug should not be prescribed simultaneously with other antiparasitic drugs to avoid increased toxic properties and accumulation.

SPECIAL INSTRUCTIONS When handling the drug, you should use rubber gloves, especially if there are abrasions and other skin damage on your hands. During treatment, drinking, smoking and eating are prohibited. Do not pet or bathe the animal or allow it near small children for 24 hours after use. If the product gets on the skin or mucous membranes, it must be washed off immediately with a stream of water or removed with a swab and then washed with water. Avoid getting the drug into the oral cavity; if it is accidentally swallowed, consult a doctor immediately. At the end of the treatment, hands should be washed thoroughly with warm water and soap.

STORAGE CONDITIONS With precautions (list B). In a dry place, protected from direct sunlight and inaccessible to children and animals, separately from food and feed at a temperature of 0 to 30 ºС. Shelf life: 2 years.

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Can it be used in pregnant cats and kittens?

Dironet in the form of a solution is contraindicated for oral use in cats in an “interesting position”, as well as in kittens under 2 months. The tablet form is not given to pregnant or lactating furry pets, or babies under 3 weeks of age. External treatment with drops can be done on babies only 2-3 weeks after their birth.

The safest type is suspension. It can be used even when the cat is carrying or feeding offspring. But the ban remains for kittens younger than 2 weeks.

Contraindications and side effects

The drug has few contraindications:

1. Both forms of Dironet are prohibited for pregnant (at any stage) and lactating cats, kittens under 3 weeks.
2. Tablets are not given to animals whose weight is less than 0.5 kg.
3. Both types of suspension are not recommended for use in cats and kittens being treated with piperazine and levamisole.
4. Dironet Junior suspension is designed specifically for small kittens, and therefore it is given to cats during pregnancy and lactation. In any case, this point is not mentioned in the contraindications for children's medicine.

If the instructions for use are strictly followed, no side effects are observed. An exception is if the animal is allergic to one of the components.

Side effects

The drug is completely safe for the cat’s body and, when used correctly, has no side effects. The only thing is that they can be caused by an overdose, as evidenced by the following signs:

• the animal begins to feel sick and vomit;
• muscle tremors occur;
• coordination of movements and orientation in space are impaired;
• excessive weakness occurs.

Suspension for kittens in a syringe

Advantages

It is no coincidence that Dironet tablets and suspension are popular with many cat owners:

1. The components of the medicine affect various internal parasites.
2. The effectiveness of this drug is higher than that of some other anti-helminth drugs. This is proven by reviews of furry pet owners on Dironet.
3. The medicine, regardless of its form, is convenient to give. The small tablet has a demarcation strip, and therefore, if necessary, it can be easily broken into halves and quarters. The suspension is sold in a dispenser syringe, and measuring the required amount of the drug is very simple. In addition, the suspension can be given directly from a syringe. If you know the exact weight of the cat and follow the manufacturer's recommendations, this completely eliminates the possibility of an overdose.

The drug Dironet Junior also has a number of advantages. It was developed specifically for babies, and therefore you can really give the suspension to kittens without fear for their health:

1. Dironet Junior does not reduce the baby’s immunity.
2. The components of the suspension not only destroy parasites, but also promote the restoration of intestinal tissue.
3. The drug acts purposefully - against helminths in the intestines. Kidney or liver diseases are not a contraindication for taking the suspension.

Analogs

Analogues of Dironet for cats are In-Up, the medicinal complex Prazicide, Advocate and Stronghold. They are similar to the drug in question in terms of the mechanism of pharmacological action and partly the active components they contain.

Analogue

Analogues and prices

The cost of Dironet tablets (pack of 6 pieces) in a veterinary pharmacy is on average 270 rubles, drops cost approximately 300 rubles. You can replace the medicine with other anthelmintics, but their cost is more expensive:

• Milbemax (a drug based on praziquantel);
• Caniquantel (contains fenbendazole and praziquantel);
• Drontal Plus (active ingredients: praziquantel, pyrantel embonate, febantel.