Advocate® is prescribed to cats for the treatment and prevention of otodectosis (Otodectes cynotis), entomosis (Ctenocephalides felis), intestinal nematodes (larval (stage L4), immature and mature phases of development of Toxocara cati and Ancylostoma tubaeforme), as well as for the prevention of dirofilariasis (larval forms Dirofilaria immitis (L3 and L4 stages).
Advocate® can be used in cats from 9 weeks of age. Treatment of cats weighing less than 1 kg, pregnant and lactating cats should be carried out with caution under the supervision of a veterinarian. Advocate® is applied to dry, intact skin in areas inaccessible to licking, directly to the skin between the shoulder blades at the base of the neck.
What to do in such a situation? To get started, we recommend reading this article. This article describes in detail methods of controlling parasites. We also recommend that you consult a specialist. Read the article >>>
Pharmacology and composition
Advocate drops for dogs are produced by the world-famous German company Bayer HealthCare AG. Veterinary products from this company are widely known in the pharmacological market and have been successfully used for years to treat and prevent diseases in animals.
The drug is a complex antiparasitic agent. It acts through the synthesis of 2 substances:
- imidacloprid: insecticide, causes the death of ticks and fleas;
- moxidectin: acts against nematodes (worms).
Imidacloprid spreads throughout the dog's skin and coat. It is released along with sebaceous secretions, penetrates the bodies of insects during bites, causing their paralysis and subsequent death. Moxidectin enters the systemic bloodstream, tissues and organs, leading to muscle innervation of nematodes and, as a result, death. Both substances protect against parasites for up to 1 month.
Moxidectin is similar in action to ivermectin. But, unlike it, it is not toxic to collies and similar breeds. Drops belong to the third hazard class - moderately hazardous substances. If dosages are observed, they do not cause side effects and are well tolerated by dogs of different breeds.
Content
1. Advocate for dogs: pharmacological effects 2. Dosage and methods of administration 3. Cost of Advocate drops in pharmacies and clinics 4. Contraindications and side effects of Advocate for dogs 5. Reviews
An antiparasitic veterinary drug is necessary to combat ticks, fleas and internal parasites that live in the pet's gastrointestinal tract. Drops against worms and fleas are developed using German equipment by the world famous company Bayer. Their cost is quite acceptable for owners of all breeds of dogs and cats. The drug is available only in the form of a solution; there are no tablets or suspensions.
Most often, the indications for prescribing a medical product are diseases such as: demodicosis, the presence of lice, detection of lice, a positive test for the presence of cestodes, nematodes, trematodes in the body, for scabies of the eyes, nose, ears. Before prescribing a pharmaceutical drug for parasites for dogs, it is recommended to undergo a comprehensive examination at a veterinarian's office. Preventive visits to the doctor are the key to your pet’s excellent health and well-being. Before using the remedy for helminths and lice, you must carefully study the instructions in order to avoid an overdose.
A dog advocate has a relatively high cost. Why the price is justified:
- The drug belongs to the fourth safety class, which guarantees no accumulation in the dog’s liver tissue, and also prevents harmful effects on the pet’s immune system.
- Anti-parasite drops have been fully tested and meet international quality and safety standards.
- They are sold in special packaging with a dispenser, which makes it convenient to measure the smallest doses.
- The medicine is used sparingly, since the effect of the drug lasts up to 4 weeks.
- The pharmaceutical product does not lose its activity even if, 2-3 weeks after application, the dog was exposed to rain or took a home bath.
- The shelf life of Advocate drops is 3 years, but all rules for storing the substance must be followed.
A combined drug with a wide spectrum of action will allow you to avoid wearing special collars, routine deworming, and unnecessary stress for your beloved pet.
Indications for use
Drops on the withers Advocate are a combined broad-spectrum antiparasitic agent. It is effective against:
- mites – demodectic, sarcoptoid;
- fleas;
- lice;
- lice eaters;
- adult and larval forms of nematodes - roundworms (toxacara, hookworm, uncinaria) and whipworms (trichocephalosis);
- dirofilaria larvae - a type of worm that affects organs: heart, lungs, eyes, etc.
The medicine is not effective against ixodid ticks and adult heartworms. Therefore, if the dog is already affected by these types of parasites, the drug is combined with other drugs.
An antiparasitic agent is used for:
- prevention of infection with helminths and ectoparasites;
- prevention of dirofilariasis;
- destruction of fleas, lice, lice, ticks, worms;
- complex therapy of otitis and allergic dermatitis caused by insects;
- treatment of sarcoptic mange, demodicosis.
Indications and contraindications
Indications for the use of the drip drug “Advocate” are the following cases:
- The need for preventive treatment of a cat or dog against parasites such as lice, fleas or ticks.
- Treatment of the consequences of subcutaneous mite infestation.
- Treatment of ear scabies.
- Treatment of infectious diseases caused by acariform mites.
- Treatment of diseases caused by different types of insects.
- Treatment of diseases of the digestive system caused by roundworms.
- Treatment of difilariasis.
Before you start using this product, you should familiarize yourself with the list of contraindications for its use, these include :
- The weight of the animal is less than a kilogram.
- Less than seven weeks old for puppies and less than nine weeks old for kittens.
- The presence of various diseases that weaken the body, the treatment of which is not directed by the Advocate.
- Pregnancy and lactation period. In some cases, the use of the “Lawyer” is acceptable and justified, but is carried out only after consultation and obtaining appropriate permission from the veterinarian.
- Concurrent use of other pharmacological agents, which contain different forms of macrocyclic lactones.
Instructions for use and dosage
Advocate drops (spot-on) are produced in various packaging according to the weight of the animal. The dosage is calculated based on their recommended norms - 0.1 ml of the drug per 1 kg of animal weight, which corresponds to 10 mg of imidacloprid and 2.5 mg of moxidectin per 1 kg.
Release form | Dose of active ingredients | Price per package for 3 pipettes | |
imidacloprid | moxidectin | ||
0.4 ml for small dogs weighing up to 4 kg | 10 mg/kg | 2.5 mg/kg | 1,100 rub. |
1 ml for medium animals weighing from 4 to 10 kg | 10-25 mg/kg | 2.5-6.25 mg/kg | 1,200 rub. |
2.5 ml for large dogs weighing from 10 to 25 kg | 10-25 mg/kg | 2.5-6.25 mg/kg | RUB 1,250 |
4 ml for giant breeds weighing from 25 to 40 kg | 10-16 mg/kg | 2.5-4 mg/kg | 1,300 rub. |
If the pet's weight exceeds 40 kg, combine two pipettes whose volume best matches the animal's weight. For example, for a dog weighing 43 kg, a combination of 4 ml and 0.4 ml drugs is suitable. And for a dog weighing 46 kg, 4 ml and 1 ml are combined.
Each package contains 3 pipettes. But in veterinary pharmacies and pet stores, tubes are sold individually.
Applying drops is no different from using similar products. Follow the step-by-step instructions:
- the animal is fixed - large dogs are held on the floor, medium and small dogs are lifted onto the table;
- open the pipette - remove the protective cap and pierce the tip of the tube with its reverse side;
- move the fur apart - the drug must get on the skin, otherwise it will flow down the fur coat and will not penetrate the body;
- examine the skin - it must be clean, dry, without damage or redness, otherwise the drops cannot be used;
- apply the medicine - drop it into 3-4 points that are inaccessible for licking (from the withers to the lower back), it is better to apply immediately behind the ears in front of the scruff of the neck.
The frequency of use depends on the clinical case and varies from 28 to 64 days. On average, the drug for dogs is recommended to be used once a month during the parasite activity season - from early spring to late autumn.
Properties and pharmacodynamics
Thanks to its balanced composition, Advocate has a pronounced insecticidal and acaricidal effect. Refers to universal, combined medications with prolonged action.
Imidacloprid is a substance belonging to the group of chloronicotinyl insecticides. The mechanism of action is based on disruption of innervation, transmission of nerve impulses of ectoparasites, as well as interaction with acetylcholine receptors of arthropod blood-sucking insects, which leads to their death.
Advocate for dogs is available in pipettes of various sizes.
Moxidectin is a semi-synthetic compound from the milbemycin group. It is quickly adsorbed through the skin, penetrates the bloodstream, is evenly distributed in the body, and provides a prolonged effect. It has a stimulating effect on the release of gamma-aminobutyric acid, which, by binding to postsynaptic receptors of ecto- and endoparasites, provokes disruption of muscle innervation, which leads to instant paralysis and death of fleas, ticks, and nematodes.
The insecticidal effect after a single treatment of dogs lasts for four to six weeks, and the acaricidal effect lasts for 28-35 days.
Price and analogues of the drug
The price of Advokat drops in different pet stores and veterinary pharmacies varies from 350 to 800 rubles. Among the main analogues of this drug, the most famous are:
- Frontline is a pretty good analogue of Advocate drops, but this product has one rather unpleasant side effect - a change in the color of the fur at the site of application.
- Celandine is an effective remedy for fleas, even kittens can be used, but it is completely useless against worms and subcutaneous parasites.
- Inspector - has the same spectrum of action as Advocate drops, therefore it is a complete analogue of the indicated product.
- Bars Forte is a domestic drug that helps well in the fight against fleas, but it will not get rid of other parasites.
Advantages and disadvantages
Advocate drops on the withers are one of the best antiparasitic remedies. It has many advantages compared to other drugs:
- complex action - one pipette kills ectoparasites and worms, which frees the animal owner from purchasing and feeding deworming tablets;
- safety;
- side effects are minor, occur rarely and go away on their own;
- allowed for use by puppies from 7 weeks;
- an abundance of dosages for dogs of different sizes;
- collies and similar breeds can be used;
- convenient use.
However, the drug also has disadvantages:
- There are often fakes - be especially careful when ordering from online stores and purchasing in small pet stores;
- high price - from 350 rubles per pipette;
- does not help against ixodid ticks;
- difficult to obtain, especially in regions and small towns - due to the high cost, not all veterinary pharmacies and pet stores purchase the drug.
Owner reviews
YuliaYa1977: “For the first time we took these drops. The dog did not struggle during treatment and behaved calmly. Overall, she tolerated the drug well - no signs of intoxication. Only the wool smells a little, but after other products the smell was stronger.”
KseniaZH: “Six months ago my pug got sick. He was still a puppy then and didn’t weigh even 4 kg. At first a small pimple appeared on my forehead, which then became covered with skin. The vet said it was a subcutaneous mite and appointed a lawyer. He said to drip for 4 months in a row every 30 days. After the second use, the crusts disappeared, and after the 4th time everything disappeared as if by hand. The price is steep, but I ordered at my own risk on the Internet: it turned out to be almost 2 times cheaper and they sent the original medicine, although I was afraid of a fake.”
Doglover27: “The drops saved us! My dog was itching endlessly. I thought it was fleas, but nothing helped. Then I suffered from a food allergy, changed my diet, and also without results. We went to the vet and he said it was itch mites. These small parasites are not visible, so they could not determine what the dog was sick with. After two applications, the animal stopped itching and suffered from itching.”
Advantages and disadvantages
Many veterinarians recommend the “Advocate” product, since it has many positive aspects.
Its main advantages include:
However, despite so many positive aspects, “Lawyer” also has certain disadvantages, they are as follows:
- Possibility of side effects.
- The odor is too strong and unpleasant, which persists for a day after treatment.
Precautions for humans
When using Advocate drops, owners should observe the following precautions:
- You can't eat, drink, smoke.
- After use, be sure to wash your hands with warm water and soap.
- The cat should not be petted during the day, and small children should also be protected from contact with it.
- In case of accidental contact with the skin or eyes, it should be washed off under running water.
- If accidentally swallowed, seek medical attention immediately.
- Empty medicine pipettes cannot be used in everyday life; they are disposed of as household waste, after being placed in a plastic bag.
Features of use and prevention
It is important to protect not only your pet, but also yourself, since “Advocate” drops, if the recommendations for use are not followed, can cause poisoning, including in humans.
- Do not apply the drug in places close to food. The best use is in an open space or room with good ventilation.
- Drinking and smoking are prohibited during the procedure.
- Handling a sick animal is carried out only with gloves, after which you should still wash your hands well with plenty of soap.
- If the active substance gets on the mucous membrane, you should immediately wash it off with plenty of water.
- If drops get inside, you need to consult a doctor for possible gastric lavage.
Careless use of the medication can lead to poisoning for both the pet and the owner.
Video - Application and effect of the drug
Limitations and side effects
Advocate drops should not be used for cats in the following cases:
- if age less than 9 weeks;
- during the recovery period after serious illnesses and operations;
- for infectious pathologies;
- if there is intolerance to the components (allergic reactions occur).
It is better not to use the drug for pregnant and lactating females. If there is an urgent need for this, the procedure should be carried out under the supervision of a doctor. If the animal has acute or chronic diseases of the heart, liver or kidneys, consultation with a veterinarian is necessary.
Animals usually tolerate the medication without problems. Sometimes vomiting, skin irritation, lack of appetite or depression occur. If the medicine is accidentally ingested, vomiting or stomach upset may occur. The drug may cause disruptions in the functioning of the nervous system. They are manifested by impaired coordination of movements, apathy and mood swings.
Advocate's analogs
Analogs of original medicines are drugs with different names and main active ingredients. The selection of analogues is carried out by a doctor.
Analogues of Advocate
Infection of pets with various parasites threatens the health of not only the animal, but also all family members. Infection with pathogens can have a particularly serious impact on the well-being of younger and older generations. Therefore, timely contact with veterinary hospitals and the use of antiparasitic drugs should not be neglected.
Table: analogues
Drug name | Active substances | Release form | Indications for use | Safety of use | Price |
Bars Forte |
| Solution in pipettes |
| Safe for the animal | From 200 rubles |
Inspector |
|
| Safely | From 300 rubles | |
Celandine |
| Solution in ampoules |
| Moderately dangerous | From 80 rubles |
Frontline |
|
| Safely | From 450 rubles |
Reviews about the use of drops
Inga
Very easy to use. I dripped it in the area of the shoulder blades, and that’s it; to consolidate the effect, you need to drip it only after a month. What can I say, it’s not for nothing that these drops are praised. Helps against ticks, fleas, and as a helminthic.
dlyusya
Advocate drops turned out to be very effective: the cat is now alert, cheerful and does not itch at all. But for the first three days after treatment, the unfortunate animal showed signs of poisoning - drooling and weakness (I even began to blame myself for killing my yard friend), but, fortunately, the symptoms went away. Perhaps this is an individual reaction (however, other drops did not have such a negative effect, cats always tolerated them perfectly), but I am afraid to take such drops again. Despite the negative experience, I will rate this very effective and easy-to-use drug 4 stars.
Olya
If you see some kind of parasite on your pet’s body, do not think that you will kill it now and that will be the end of all problems: insects multiply very quickly, and before you know it, a whole settlement will appear on the cat. Therefore, immediately buy a remedy for blood suckers. This may not be Advocate, but it should be effective, so when purchasing the drug, consult at least with a veterinary pharmacy employee.
Answers to frequently asked questions
When can you bathe your dog?
It is advisable not to wash your dog with shampoo for 4 days before and after treatment. Detergents break down the lipid layer, which reduces the effectiveness of the flea and tick product. Although bathing does not affect the anthelmintic effect of the drug.
If the dog got caught in the rain, ran through puddles, or jumped into a pond for a couple of minutes, it’s okay. The effect of the drops will continue.
The dog weighs less than the minimum dosage - up to 4 kg. How to proceed?
For animals weighing over 1 kg, the entire 0.4 ml pipette can be used under the supervision of a veterinarian. As a rule, the medicine does not cause side effects. If the dog weighs less, a lawyer cannot be used.
I have two dogs weighing about 20 kg. Is it possible for them to take one pipette for giant breeds (weighing up to 40 kg) and divide it equally?
You cannot divide the pipette - this makes it impossible to calculate the correct dosage. For each dog, a release form is purchased that corresponds to its weight.
Does Lawyer help against ixodid ticks?
The drug is not effective against ixodid ticks. To destroy this type of parasite or prevent infection by it, Advantix is first used. And after 2-7 days they use Advocate.
Can it be used in conjunction with other antiparasitic agents?
Drops cannot be used along with similar drugs. The exception is Advantix and the Foresto collar. They contain different active ingredients and together protect against all types of parasites.
It is possible to defeat parasites!
Antiparasitic Complex® - Reliable and safe removal of parasites in 21 days!
- The composition includes only natural ingredients;
- Does not cause side effects;
- Absolutely safe;
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- Effectively destroys most types of helminths in 21 days.
There is now a preferential program for free packaging. Read expert opinion.
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Information about the drug Advocate for dogs
The trade name of the product is Advocate®, and the international non-patented name is based on the names of its main active components:
- imidacloprid (100 mg in 1 ml of product);
- moxidectin (25 mg per 1 ml of product).
The only dosage form in which the drug is produced is a solution intended for external application. Here are the excipients contained in the composition:
- Propylene carbonate (weight - 165 mg);
- Benzyl alcohol (weight - 807 mg);
- Butylated hydroxytoluene (weight - 1 mg).
The release form of the drug is drops (spot-on), they are pre-packaged in polymer pipettes, which are packaged in special blisters made using aluminum foil, 3 pieces each. Next, these blisters are placed in boxes, and the instructions also go there.
Advocate remedy for dogs must be stored only in the closed packaging in which the drug is supplied; it is important that it is placed in a dry place, protected from direct sunlight. The manufacturer also notes that it cannot be stored next to dog food or other products, and the permissible storage temperature ranges from 0 to 30 degrees.
If you comply with all the conditions discussed earlier, then the shelf life of the product will be exactly 3 years from the date of production (the date is indicated on the box). Use after the expiration date is strictly prohibited; do not risk the health of the animal. Storage should take place in a place where children do not have access, and the Lawyer should dispose of it according to the rules given in the legislation.