Frontline: insectoacaricidal drops and spray to combat ectoparasites and helminths of cats, dogs and ferrets

Precautionary measures

As mentioned above, the medication is one of the drugs that is low-risk for the body of dogs.
Complies with GOST standard 12.1.007.76 However, when working with Frontline, as with any medicine, precautions should be taken:

Strictly observe the dosage of the drug. Do not use in conjunction with an anti-parasitic collar. Observe age restrictions on the use of the product. Use with caution on weakened and older dogs. Use with caution for pregnant and lactating individuals. If possible, during these periods, avoid any chemical exposure without special indications. Be sure to check with your veterinarian about possible interactions between fipronil and other medications. Before use, you should make sure that the dog does not have an individual intolerance to the components of Frontline.

Instructions for use and precautions

Treatment is carried out outdoors and indoors with open windows or a ventilation system that provides a good flow of fresh air. It differs for different release forms.

Drops are applied to the animal’s withers, after spreading the fur. You need to try to get the liquid directly onto the skin. Sprays are sprayed against hair growth. Tablets are given orally.

When treating, a few drops are instilled directly into the animal's ear. After this, the ear is folded in half and lightly massaged for better penetration of the substance. When applying the composition, it is necessary to avoid getting it into the animal’s mouth or eyes. To do this, before using the spray, moisten the area around the eyes, nose and mouth with clean, cool water. If trouble cannot be avoided, you should rinse off the remaining substance with plenty of water to relieve your pet of the tingling sensation caused by the substances included in the composition.

After the product is applied, the animal is held until the fur dries. This will avoid the transfer of active substances to pieces of furniture. You should also isolate the animal from contact with children for a day. At this time, it is better to refrain from playing with your pet and stroking it.

The maximum effect is achieved one day after application. It is allowed to wash your pet no earlier than 48 hours after the end of the procedure.

If there are several animals in one apartment, it is better to carry out preventive procedures for all on the same day. For prophylaxis, Frontline is used every 4 weeks. If the animal is bathed daily, it is recommended to reduce the time interval between treatments.

If the drug comes into contact with exposed skin of the person carrying out the treatment, the stained area should be washed with plenty of running water. Empty Frontline bottles are strictly prohibited from being reused for storing any substances or for other household purposes. After use, the empty container is tightly closed with a lid, packed in a plastic bag and thrown into the trash.

Composition and release form of the drug Frontline

To combat skin parasites of cats, the French corporation Merial SAS created the drug Frontline. The company conducts serious research and has a strong reputation in the market for manufacturers of veterinary drugs.

The drug is available in three dosage forms:

• drops in polyethylene pipette bottles with a volume of 0.5 to 4.02 ml;
• spray in bottles with a sprayer of 100, 250 and 500 ml;
• Chewable tablets (for dogs only)

Table: dosage forms for cats

Photo gallery: release forms

Active ingredients of the veterinary drug Frontline:

• Fipronil has a detrimental effect on the central nervous system of parasites, disrupting the movement of nerve impulses. Causes paralysis and subsequent death of insects. Fipronil does not have a systemic effect on the body of a pet, destroying only pests.
• S-methoprene (as part of Frontline Combo) is an analogue of the hormone-regulator of insect growth, causes developmental anomalies at the egg and larval stages, prevents the appearance of adult individuals on animals and in places where they are kept.

Additionally, Frontline contains excipients:

• in the spray - isopropanol, copolyvidone, purified water, polysorbate;
• in drops on the withers - butylated hydroxyanisole, butylhydrotoluene, diethylene glycol, polyvidone, polysorbate.

The content of the active substance in any form ensures effective destruction of parasites.

Frontline combo

The working fluid is poured into pipettes with a volume of 0.5; 0.67; 1.34; 2.68; 4.02 cm3.

Cost in September 2022 - 605 rubles.

Frontline combo destroys lice eaters, fleas, ixodid and sarcoptic ticks, and mosquitoes. The treatment destroys ticks within 48 hours and other insects within 24 hours.

The tip of the Frontline combo pipette is broken off and squeezed onto clean, intact skin in places that are inaccessible for licking. The drug protects against attacks by ixodid ticks for 4 weeks. The repellent time against fleas and lice for cats and ferrets is 42 days, for dogs - 12 weeks. The drug is used as needed, at intervals of at least three weeks.

Dosage the insectoacaricide according to the scheme:

Frontline is not prescribed to puppies up to 2 kg, kittens up to 8 weeks and weighing up to 1 kg, ferrets up to 6 months. The drug is prescribed to lactating animals under the supervision of a veterinarian. The female is isolated from the cubs for half an hour or more until the applied insectoacaricide dries. Frontline combo is toxic to decorative rabbits. After treatment, the pet should not be allowed to get wet for two days.

The drug is stored for 3 years at temperatures from 0 to 30 °C.

Directions for use and dosage

Sprays and drops on the withers are applied only externally, to the skin. The skin of the animal being processed must meet the following requirements:

It should be dry.

It is highly desirable that the skin be clean. The purer it is, the more evenly the medicine will be distributed throughout it, and the more pronounced its effect will be. Veterinarians advise washing your pet before treatment. The use of shampoos with an antiparasitic effect is not prohibited, but before doing so, you should consult a veterinarian (to avoid drug incompatibility).

It cannot have cuts, scratches, areas of inflammation or other types of erosion. Otherwise, the risk of poisoning increases sharply (the pure drug should not end up in the general circulation).

If there is a rash or signs of dermatitis on the skin, or there are other symptoms of allergic pathologies, the use of the drug should also be postponed “until better times.”

The spray is somewhat easier to use: it is used to evenly irrigate the pet’s fur on all parts of its body. True, after this the cat will need to be occupied with something for about an hour so that she does not have time for licking.

In the case when chewable tablets are used, the cat should not have pathologies of the digestive system, that is, constipation or diarrhea. In addition, it is highly undesirable to treat animals (regardless of the dosage form used) suffering from acute or chronic liver and kidney diseases.

Application of drops/spray

In such cases, the medicine is applied to the withers, between the shoulder blades. The fur needs to be parted (we remind you that it must be clean), after which the required volume of the drug is applied to the exposed skin.

When treating ear mites, everything is somewhat more complicated:

It is necessary to clean the ear canals from deposits of mite waste products. To do this, you can use either 3% hydrogen peroxide or sterile vegetable oil (you can make it yourself by “calcining” the oil in a water bath). Regular cotton swabs are ideal for this purpose. You need to clean your ears carefully, being careful not to damage the ear canal or eardrum.

After this, you need to drop a couple of drops of medicine into each ear canal. Plug the ear canal for about a minute with a finger, while lightly massaging the skin at the base of the ear. These actions help the medicine to be distributed more evenly, which significantly increases the effectiveness of treatment.

For treating cats, we recommend using only 0.5 ml pipettes. In this case, the dosage is extremely simple: one dispenser per animal.

Use of chewable tablets

With them everything is much simpler: the drug is given once, orally, always with food.

But! Considering the variety of packaging, release forms and concentrations of the active substance, we can give only one piece of advice: carefully read the instructions for use included with the medicine by the manufacturer! With tablets, everything is much simpler: the medicine is given at the rate of 2.5 mg of active substance per kilogram of live weight.

Overview of the features of the Frontline action

Frontline refers to products used to eliminate and prevent the appearance of ectoparasites in cats and dogs. The drug has a superficial effect. After use, the components of the drug do not enter the blood, but are distributed over the surface and accumulate in the sebaceous glands. From these, the drug is gradually applied to the skin in the amount necessary to destroy parasites. Thus, after a single treatment, the effect of the drug remains for a fairly long period.

Fleas on a cat

Frontline destroys the following types of skin parasites:

• fleas;
• ixodid ticks;
• cheilitels;
• otodexodes;
• lice eaters;
• lice.

Life cycle of a dog flea

Frontline is produced in several forms, allowing you to choose the one that will be convenient to use for the animal owner.

Frontline composition

The main substance that provides the insecticidal effect of the drug is fipronil. In addition, in various forms of release, Frontline can be supplemented with several substances to enhance effectiveness. Among them:

• butylated hydroxyanisole;
• ethanol;
• butylated hydroxytoluene;
• excipient.

Chemical formula of finpronil

Pharmacology

Fipronil, which is the basis of the drug, affects insect receptors, disrupting the movement of impulses. This causes paralysis and subsequent death of the arthropods.

Frontline is active against almost all common skin parasites of animals. Accumulating in the hair follicles, epidermis and sebaceous glands, fipronil enters the animal’s skin along with the secretion. The effect occurs after 24-48 hours. During this time, the parasites present on the animal die, and the drug is completely absorbed into the skin. The protective properties last for a period of 15 to 45 days. The duration of exposure largely depends on the size of the animal, characteristics of care and accommodation.

The structure of a dog's skin

Contraindications and side effects

After the studies, no obvious side effects or contraindications to the use of the drug were identified. The manufacturer recommends refraining from treating kittens weighing up to 1 kg with the universal product to avoid overdose. If there is a need to process them, it is better to use Frontline, created for small animals. The concentration of the active substance in such preparations is significantly lower than in products for adults. They have a gentle effect on the still fragile body.

Treatment of a kitten with Frontline, created for small animals

It is also recommended to avoid using the product on animals with damaged skin. Multiple wounds can lead to penetration of the active substance into the blood. This will not cause any negative effects on your pet, but may cause minor short-term deterioration in well-being.

Contraindications

The drug Frontline is not toxic to cats, so the list of contraindications for using the drug consists of only two points:

• Individual intolerance to the drug in animals;
• The age of the kitten is 1 day after birth.

Possible side effects:

Hypersalivation.

Important!

If side effects occur, you should immediately stop using Frontline and wash it off your pet's fur. In case of severe allergic reactions, it is necessary to consult a veterinary doctor for help and administer anti-allergy drugs.

In addition, when choosing a particular product, it is important to pay attention to what age or weight of the animal it is intended for. The product range of this manufacturer allows you to select suitable drugs for both adults and kittens. This is especially convenient for those owners who have not one cat, but several pets of different ages.

This is especially convenient for those owners who have not one cat, but several pets of different ages.

In the range of the series you can find:

By the way, Frontline drops and sprays intended for cats can also be used for ferrets, which are increasingly found as pets. What are the specific features of certain Frontline tools?

How to distinguish the original Frontline from a fake?

Frontline is a sought-after and popular drug, sold in many countries around the world. Like other effective medicines, it is also often counterfeited for profit.

You can distinguish an original from a fake if you know certain differences between them.

• Even single doses of the product are packaged in individual cardboard boxes. If a pet pharmacy offers to purchase a separate plastic pipette, explaining this as a wholesale purchase from the store in order to reduce the cost of products, it is advised to refuse the purchase.
• The original Frontline drops have their logo (on the dropper).
• The original box contains an indication of the batch number and the specific date, as well as the expiration date. The lot number must be indicated on the plastic applicator.
• Each package contains an insert with detailed instructions for use and information on first aid for your cat if side effects occur.
• The applicator is additionally sealed in plastic to protect it from children.
• There are no holograms or stickers on the packaging.
• On the back of the applicator you can find the name of the manufacturer Merial, the name and shape of the product, a note stating that the drug is for external veterinary use only, the concentration of the active component, and the amount of solution in the pipette.

Products imported to the Russian Federation from France (the drug is manufactured in France) may bear the PCT mark. The appearance of paper boxes from different batches may differ; in particular, manufacturers change the color design and photographs of cats.

Frontline Spray flea and tick spray for dogs and cats

Considering that this product can be used on cats and dogs of different ages and weights, it is necessary to study the attached instructions in detail. It describes in detail how many clicks need to be made to spray the body of an animal that has a specific size, weight, and coat length. Despite the comparative safety of this insecticide, it is still a poison, which means you should not overdo it when spraying your pet with it.

Frontline insecticidal sprays are sold in bottles of 100 and 250 ml. For cats, given their smaller size compared to large dog breeds, it is more advisable to buy the first option. At the same time, if you need to regularly treat a large number of cats and kittens, you can buy a 250 ml bottle.

There are some precautions to using the spray. So, it is advisable to apply the product to animal fur outdoors. In the case of cats that are not allowed outside, this can be problematic. In such situations, the spray should be used in a well-ventilated area, preferably on a balcony, veranda, etc. It is better not to spray the spray on the animal’s face, because it can get into the eyes and mucous membranes of the mouth and nose.

Frontline Nexgard chewable tablets for dogs

There are situations when it is very inconvenient or even contraindicated to use external means to combat the parasite. For example, there are wounds on the dog’s skin or you bathe him often and therefore the drops are not effective. Frontline Nexgard chewable tablets will come to your aid.

You will immediately cope with two tasks: firstly, get rid of external parasites; Secondly, the tablets act on worms inside the animal.

Nexgard chewable tablets for fleas, ticks and worms contain the active ingredient afoxolaner. The medicine tastes like beef stew, so dogs eat it with pleasure.

The effect of the medication begins within half an hour after administration. Complete destruction of parasites occurs within 6-48 hours.

It is very convenient that you only need to use the tablets once a month.

Instructions for use

The manufacturer took care not to calculate the dosage of the drug. You just need to weigh your pet and buy the necessary box. There are 4 types of tablets, depending on the weight of the animal: from 2 to 50 kg. Per 1 kg of animal weight, 2.5 mg of afoxolaner is required.

Give the medication separately or with food. Do not break the tablets or they will no longer be effective. The medicine is contraindicated in dogs weighing up to 2 kg or under 2 months of age. Give medication to pregnant and lactating females only with the consent of the veterinarian.

Frontline is an effective insect repellent for dogs. When choosing a form of medication, rely not only on ease of use, but also on existing contraindications, the age of the animal and the degree of infection.

There is also a separate form of Frontline for cats.

Release form

Frontline is a French antiparasitic product from the company Merial, it has a low degree of toxicity, and is safe for puppies and pregnant females. You can buy it at almost any veterinary pharmacy. The main active ingredient in the drug in liquid form is fipronil, which effectively destroys all types of ticks, fleas, ear scabies, and lice-eaters. The composition of the medicine in other forms is slightly different.

Release form:

1. Spray for treating fur - produced in bottles with a sprayer of 100 or 250 ml, can be used to treat puppies within 48 hours after birth. Price – 1.2–2 thousand rubles, depending on volume.
2. Spot it - drops on the withers, they go on sale in plastic disposable pipettes, which differ in dosage. You can choose a product for puppies, small, medium and large dogs weighing 2–60 kg. Price – 500–600 rub. for 1 dose of the drug.
3. Spot on Combo - drops. In addition to fipronil, the composition includes S-methoprene. Can be used to treat animals from 2 months of age with a body weight of more than 2 kg. Cost – 400–800 rubles, depending on volume.
4. Nexgard - chewable tablets, have a pleasant smell of meat, contain afoxolaner, protect the animal from fleas and ticks, worms. Can be used to treat pets older than 8 weeks, weighing more than 2 kg. Price – 600–800 rub.
5. Tri-Act repellent, repels flies, mosquitoes, mosquitoes, contains permethrin and fipronil. The drug has a fast action, fleas die within a few minutes after treatment, ticks die within 6 hours. Apply to the head and withers. Safe for pets older than 8 weeks and weighing more than 2 kg. Price – 500–700 rub. depending on dosage.

The active substances of the medicine have a detrimental effect only on parasites. At the same time, they penetrate into the general bloodstream when taken internally in a minimal amount, do not disrupt the functioning of the vital organs of a dog or cat, and are gradually eliminated from the body naturally.

Operating principle

After treating the animal, the active substance disrupts the functioning of the nervous system of the parasites, causing paralysis, which leads to the rapid death of the insects. The solution has a fine, oily consistency, which allows it to be evenly distributed throughout the coat. The active ingredients accumulate in the sebaceous glands, so Frontline provides long-term and reliable protection for the animal against re-infection, against ticks for 4 weeks, and against other insects for 8-10 weeks.

Frontline Combo is used to treat severe forms of invasion. The substance S-methoprene is able to penetrate the chitinous layer of parasite eggs and enhances the therapeutic effect of fipronil.

Frontline destroys adults and larvae at all stages of development.

Recommendations

There is no need to bathe the animal 2 days before and 2 days after treatment. Until the fur is completely dry, you need to make sure that the animal does not lick the drug. Also, do not allow it near heating devices or open fire. Young children should be excluded from contact with the animal for 24 hours. During this time you cannot pet him. To avoid re-infestation and prevent fleas from breeding, the bedding should be replaced. In addition, the following rules must be observed:

• after applying the spray, you should wash your hands with soap;
• when applying the product, do not eat, drink or smoke;
• the drug should be stored out of the reach of children.

High effectiveness of the drug is achieved by following the recommended regimen of its use. When using the product, you should not use other insectoacaricidal drugs.

Indications for use Frontline

The action of the drug Frontline in various forms of release is aimed not only at the complete destruction of ectoparasites, but also at preventing the reproduction and further development of parasites in the house.

The advantages of Frontline are:

• elimination of ticks, fleas and lice eaters on the animal’s body within 24 hours;
• protection for 30 days after one-time treatment;
• safety for all types of cats, regardless of coat thickness and age.

Indications for the use of Frontaline are:

• elimination of temporary ectoparasites – fleas;
• protection against ticks and lice;
• elimination of lice and ear scabies pathogens.

Contraindications and side effects

Frontline is extremely toxic to rabbits. It is not allowed to use the product on kittens under 8 weeks of age and babies weighing less than 1 kg. The drug should not be used for pets who are weakened after serious illnesses, or if there are lesions on the cat’s skin.

The use of Frontline is not recommended for:

• individual intolerance to the components of the product;
• hypersensitivity to the components of the drug;
• allergic reactions.

Side effects from using Frontline medicines are rare. The animal's skin in the area where the drops are applied may temporarily become discolored or red, hair may fall out, or itching may occur. Allergic reactions can be eliminated by bathing the cat with shampoo and giving antihistamines.

Analogues of the drug

When choosing analogues of Frontaline, it is necessary to note the effectiveness, as well as the smallest number of side effects that occur when treating cats.

Potential analogues of Frontline are the following insectoacaricides:

• Advantix drops (Bayer, Germany);
• Bolfo spray (Bayer, Germany);
• Ultra Guard drops (Hartz, USA).

Before starting to use any type of antiparasitic medication, you should always consult with a veterinarian.

Sources

• https://dezplan.ru/vopros/frontlayn-ot-bloh
• https://vashipitomcy.ru/koshki/lechenie_i_profilaktika/frontlajn-dlya-koshek-instrukciya-po-primeneniyu/
• https://www.parazitty.ru/kleshi/frontlajn-tabletki-ot-kleshej-dlya-sobak/
• https://apest.ru/kleshhi/sredstva-ot-kleshhej/frontlajn-ot-kleshchej/
• https://usobaki.com/frontline-for-dogs/
• https://PetGuru.ru/zdorovie/frontlajn-dlya-sobak
• https://apest.ru/blohi/sredstva-ot-bloh/frontline-ot-bloh/
• https://okotikah.ru/preparaty/frontlajn-dlya-koshek.html
• https://101kote.ru/stati/frontlayn-dlya-kotov-i-koshek.html

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special instructions

If there is increased individual sensitivity to the components of the drug and signs of allergic reactions appear, the treatment is stopped, the drug is washed off with water, and antihistamines are given orally. + When working with Frontline Combo, you should follow the rules of personal hygiene and safety precautions provided for working with medicinal products for animals. While working with the medicine, you are not allowed to drink, smoke, or eat. If Frontline Combo accidentally gets on the skin or mucous membranes, it should be washed off with a stream of water. After finishing work, wash your hands with warm water and soap. Empty drug pipettes must not be used for household purposes; they must be disposed of with household waste.

Release form:

FAQ

Can it be used by animals during pregnancy or lactation?

According to the results of numerous international tests, experts have not identified any negative effects on this category of pets. Frontline is the only insecticidal and acaricidal drug whose use is permitted during these periods. In order to treat kittens under 2 months old, the company produces it in the form of a spray.

Is it dangerous if a pet licks its fur after treatment with Frontline?

No. The drug is not dangerous to life and will not cause harm to the body, however, if it gets inside the body, it can cause excessive salivation, so to avoid this situation, you need to apply the product to those places where the cat cannot lick it off.

Experts advise using the drug to treat cats every 2 months, during periods of danger of infection. If there is a danger of ticks, then the procedure must be repeated every month no more than once.

Does Frontline repel or prevent tick bites?

No. The medicine does not affect the bite. It prevents the transmission of diseases from ticks to pets. The fact is that a tick needs from 48 to 72 hours to infect an animal - this is the time for transmission of infection. During this time, Frontline neutralizes the impact of the tick on the body.

The cat got wet or dirty after using the product, can it be washed?

Yes. The medicine is resistant to an aqueous environment, however, it should be left for 48 hours until the drug is absorbed into the skin. If the pet is washed more than 2 times a month, then treatment should be carried out more often.

Is there a need to take funds in parallel with Frontline?

A medicinal insectoacaricidal preparation in the form of a solution for external use, containing fipronil - 9.8% and S-methoprene - 8.8% as active ingredients, and polyvidone and polysorbate as excipients.

Indications for use

Used to combat fleas, lice, lice and ticks (ixodidae, cheylitella) of cats by topical (Spot On) application to the skin.

Dosage and method of administration

Frontline Combo is used to combat fleas, lice, lice and ticks (ixodidae, cheylitella) in cats by topical (Spot On) application to the skin. Before treatment, break off the tip of the pipette, spread the animal’s fur in the back area (between the shoulder blades) and, pressing the pipette, apply the drug to the skin at one or several points. The protective effect of the drug against ixodid ticks in cats lasts up to 3 weeks, against the imago and preimaginal phases of insect development up to 6 weeks. If the animal is severely affected by lice, fleas, lice, it is recommended to treat once a month. If the animal is washed more than 2 times per month, it is recommended to reduce the interval between treatments to 3 weeks. It is not recommended to wash animals within 48 hours after treatment with Frontline Combo, or to use other insectoacaricidal agents.

Side effects

In terms of the degree of impact on the body, Frontline Combo is a low-hazard substance (hazard class 4 according to GOST 12.1.007.76), in recommended doses, it does not have a skin-resorptive, sensitizing, embryotoxic, teratogenic or mutagenic effect. In case of contact with eyes, it causes mild irritation.

Contraindications

Increased individual sensitivity to the components of the drug. Sick and convalescent animals, as well as kittens under 8 weeks of age, cannot be treated.

Frontline Spot On

Instructions #

for veterinary use Frontline Spot On

(developer organization: Boehringer Ingelheim Animal Health France SCS, 29 avenue Toni Garnier, 69007, Lyon, France / Boehringer Ingelheim Animal Health France SCS, 29 avenue Top Gamier, 69007, Lyon, France)

I. General information

1. Trade name of the medicinal product: Frontline Spot On. International nonproprietary name: fipronil. 2. Dosage form: solution for external use. Frontline Spot It contains fipronil as an active ingredient - 10%, and as excipients: ethanol, povidone, polysorbate 80, butylated hydroxyanisole, butylated hydroxytoluene, and diethylene glycol monoethyl ether. 3. In appearance, Frontline Spot is a transparent solution from yellow to brown. The shelf life of the medicinal product, subject to storage conditions, is 3 years from the date of manufacture. After opening the pipette, the drug cannot be stored. It is prohibited to use the medicine after the expiration date. 4. Frontline Spot is released packaged in 0.5; 0.67; 1.34; 2.68 and 4.02 ml in pipettes made of thermoformed shell (polypropylene and polyacrylonitrile-methylacrylate copolymer) and film (polyethylene terephthalate, aluminum and polyacrylonitrile-methylacrylate copolymer) with a break-off tip, placed individually in blisters along with instructions for use. 5. Store the medicinal product in the manufacturer’s sealed packaging, separately from food and feed, in a place protected from direct sunlight, at a temperature not exceeding 30°C. 6. Frontline Spot It should be kept out of the reach of children. 7. Unused medicinal product is disposed of in accordance with legal requirements. 8. Frontline Spot It is available without a veterinarian's prescription.

II. Pharmacological properties

9. Frontline Spot On is an insectoacaricidal drug with contact action. 10. Fipronil is an insectoacaricide of the phenylpyrazoles group, the mechanism of its contact action is to block GABA-dependent arthropod receptors, disrupt the transmission of nerve impulses, which leads to paralysis and death of ectoparasites. Frontline Spot It is active in relation to:

• mature fleas Ctenocephalides spp.;
• lice eaters Trichodectes canis, Felicola subrostratus, ixodid ticks (all phases of development) Rhipicephalus sanguineus, Dermacentor variabllis, Atblyuotta americanum, Ixodes /10/ocyclus, Ixodes scapularis, Ixodes ricinus, Haemaphysalis spp. including Haemaphysalis longicornis, Haemaphysalis flava, Haemaphysalis campanulata, Haemaphysalis leachi;
• lice Linognathus setosus;
• scabies mites Sarcoptes scablei var. canis;
• mosquitoes Aedes aegypti.

After applying the drug to the skin, fipronil is gradually distributed over the entire surface of the body within 24 hours and, practically without being absorbed into the systemic bloodstream, accumulates in the epidermis, hair follicles and sebaceous glands, has a long-term contact effect (up to 56-60 days), is metabolized to form derivatives (mainly sulfones) active against ectoparasites. A single treatment of the animal ensures the destruction of fleas and ticks within 24 - 48 hours. After treating cats, the protective effect against ticks lasts up to 4 weeks, against insects - 4-6 weeks. After treating dogs, the protective effect against ticks lasts up to 5 weeks, against insects - 4-12 weeks. Frontline Spot In terms of the degree of impact on the body, it is classified as a moderately hazardous substance (hazard class 3 according to GOST 12.1.007-76), in recommended doses it does not have a skin-irritant or resorptive-toxic effect, does not have an embryotoxic or teratogenic effect, if ingested causes mild irritation to the eyes. The drug is toxic to rabbits, as well as fish and other aquatic organisms.

III. Application procedure

11. Frontline Spot It is prescribed to dogs and cats, including pregnant and lactating animals, for entomosis, otodectosis, tick infestation, as well as in the complex therapy of allergic dermatitis caused by fleas. 12. Contraindication for use is the animal’s increased individual sensitivity to the components of the drug (including a history of it). The use of Frontline Spot On is prohibited for patients with infectious diseases, convalescent and weakened animals, puppies and kittens under 8 weeks of age, dogs weighing less than 2 kg, cats weighing less than 1 kg. If the eardrum is perforated, auricular use of the drug in the treatment of otodectosis is not allowed. Do not allow the drug to come into contact with the mucous membrane of the eyes of animals, and also do not apply the drug to wet or damaged skin. 13. When working with a medicinal product, you should follow the general rules of personal hygiene and safety precautions provided for when working with medicinal products for veterinary use. When carrying out therapeutic and preventive measures using Frontline Spot It is recommended to use rubber gloves. Smoking, drinking and eating are not allowed during work. When finished, wash your hands thoroughly with warm water and soap. Children should not be ironed or allowed to come into contact with treated animals, animals should not be allowed into bed with people until the area where the drug is applied is completely dry (within 24 hours after treatment), and persons with signs of allergic, respiratory and skin diseases should be allowed to work with the drug. People with hypersensitivity to the components of the drug should avoid direct contact with Frontline Spot On. If the drug accidentally comes into contact with the skin or mucous membranes of the eyes, they should be rinsed with plenty of water. If allergic reactions occur or if the drug accidentally enters the human body, you should immediately contact a medical facility (have instructions for use or label with you). It is prohibited to use empty drug pipettes for household purposes; they are placed in a plastic bag and disposed of with household waste. 14. Frontline Spot It can be used to treat breeding animals, pregnant and lactating females. 15. Frontline Spot It is used in animals by a single topical application to dry, intact skin, using pipettes of various packaging. Before processing, remove the pipette from the blister, lightly tap the drug into the expanded part of the pipette, and break off the tip of the pipette along the notch line. Spread the animal's fur at the base of the neck between the shoulder blades (in the withers area) and, pressing the pipette, apply the drug to the skin in one place in a minimum dose of 0.067 ml/kg for dogs and 0.05 ml/kg for cats, according to the table. When treating dogs weighing more than 60 kg, a combination of pipettes of different sizes is used. To treat cats weighing more than 10 kg, use 2 pipettes with a volume of 0.5 ml.

Repeated treatments of animals are carried out according to indications, but not more than once every 4 weeks. In order to prevent re-infestation of animals with fleas, it is recommended to treat all cats and dogs living together, as well as replace bedding or treat them with an insecticidal agent in accordance with the instructions for its use. To treat otodectosis, Frontline Spot He is instilled once into each ear, 4-6 drops (the drops must be injected into both ears). To distribute the drug evenly, fold the auricle in half and lightly massage its base. The remainder of the drug in the pipette used (based on the weight of the animal) is applied to the skin between the shoulder blades. When otodectosis is complicated by otitis, antimicrobial and anti-inflammatory drugs are prescribed. Animals should not be washed or bathed or allowed into natural bodies of water for 48 hours after treatment. 16. When using the drug in accordance with these instructions, side effects and complications in animals, as a rule, are not observed. Very rarely, hair may stick together at the site of application of the drug, a mild skin reaction (skin discoloration, itching, hair loss, redness of the skin), general itching or alopecia, and if the drug is ingested, excessive salivation. In exceptional cases, excessive salivation, reversible neurological symptoms (hypersthesia, depression, neurological signs), vomiting or respiratory symptoms may occur. In case of increased individual sensitivity and the occurrence of allergic reactions, the drug should be washed off with water and detergent and, if necessary, antihistamines should be prescribed. 17. With a significant overdose, the animal may experience excessive salivation, muscle tremors, vomiting, disturbances in the respiratory system, and hyperesthesia. In this case, the drug is washed off with water and detergent, and the animal is prescribed antihistamines and symptomatic therapy. 18. Frontline Spot It should not be used together with other insectoacaricidal preparations for treating animals. 19. No specific effects of the drug upon its first use and discontinuation have been identified. There may be a wet or oily spot on the animal's fur for 24 hours after application of the drug. 20. Violations of the drug use regimen should be avoided, as this may lead to a decrease in its effectiveness. If the next treatment is missed, it should be carried out as soon as possible in the same dose. 21. Frontline Spot It is not intended for processing food producing animals.

Names and addresses of production sites of the manufacturer of the drug for veterinary use: Boehringer Ingelheim Animal Health France, 4 Chemi du Calquet, 31000 Toulouse, France / Boehringer Ingelheim Animal Health France, 4 chemin du Calquet, 31000, Toulouse, France

Name, address of the organization authorized by the holder or owner of the registration certificate of the medicinal product to accept claims from the consumer/Importer: Boehringer Ingelheim LLC, Russian Federation, 125171, Moscow, Leningradskoe Shosse, 16A, building 3 Tel.

Are Frontline drugs safe?

• If the doses and rules of use are followed according to the instructions, the drug Frontline can rarely cause a negative reaction in the cat’s body, except in cases of individual intolerance to the components of the product in animals.
• However, when using the spray, the animal may experience short-term shortness of breath due to the large amount of liquid entering the animal's lungs.
• A double dose of the product, which the pet owner can use to enhance effectiveness, can harm the cat. The active component fipronil, in overdose, can cause tremors, convulsions and ataxia.
• If a kitten is treated with a single dose, there is a risk of developing intoxication.
• To prevent the drug from getting inside, it is recommended to put a protective collar on the animal, at least for a few hours.

Advantages and disadvantages of Frontline drugs

Frontline drugs have many fans among dog breeders, but due to frequent counterfeits, many pet owners prefer to use cheap analogues that are counterfeited less often.

Flaws:

• high cost, processing large dogs is expensive;
• the drops reliably protect against fleas, but the animal can become infected with ticks after 3 weeks;
• medications do not always help when a pet is severely infected.

The main advantage of the drugs is their rapid action, almost complete absence of side reactions, and can be used for newborn puppies, during pregnancy and lactation. Medicines are produced in different forms and dosages, they can be used for therapeutic and prophylactic purposes.

Frontline antiparasitic agents are popular among veterinarians and pet owners; the medications are effective and safe; negative reactions after treatment rarely occur.

Answers to popular questions

Many cat owners are interested in questions related to the nuances of using Frontline

Since the cat is a member of the family, and the health of the pet is under the close attention of the owners, they are looking for answers to their questions related to the treatment of the cat’s skin and further actions

Is it possible to scratch after treatment?

After treatment, touching the cat is not allowed. The procedure must be carried out with rubber gloves to prevent contact of the substance with your hands. The drug is applied to the clean skin of the cat, from where, due to its accumulative properties, it is gradually absorbed into the sebaceous glands, mixed with skin secretions and acts on parasites, causing their death. If you scratch your cat after applying the drug, microcracks may form, through which the product will enter the bloodstream and cause a negative reaction.

Can it be used on a dog?

It is perfectly acceptable to use Frontline on a dog. The manufacturer produces a separate type of drug in the form of a spray and drops, intended for treating dogs. The amount of medication used depends on the dog's weight.

Is it possible to divide by less?

When separating the contents of the pipette, there is a risk of violating the dosage of the active component and the alcohol-containing element, which will lead to the ineffectiveness of the medicine.

Is it okay for pregnant cats?

The drug Frontline has been tested in clinical conditions and is considered an absolutely safe treatment for cats during pregnancy.

Is it possible to put drops in the ear?

You can put Frontline drops into your ear if you are infected with ear mites. The procedure must be performed by a veterinarian in a clinic setting. The ears must be clean so that no dirt remains deep in the ear.

To treat ear mites, a spray is also used, which is sprayed into the auricle after preliminary cleaning.

Is it possible to pet a cat?

Touching a treated cat is prohibited, especially for children and people prone to allergies. The cat should not be petted until the area where the drug is applied is completely dry (about 24 hours). It is not allowed to take a treated animal into bed.

Is it possible to wash a cat?

Bathing with (or without) shampoo 1 hour before treatment does not affect the effectiveness of the drug, provided that the pet’s fur and skin are completely dry. Washing or bathing the cat is allowed 48 hours after treatment.

Advantages of the drug

The drug Frontline for treating the skin of cats and kittens is considered the most effective means for combating parasites.

The main advantages of the drug include high quality, reasonable price, effectiveness and lack of toxicity. The advantages of this product also include the absence of contraindications, the possibility of use during pregnancy and lactation, and the possibility of using the drug to treat kittens starting from two months of age.

Another advantage of the antiparasitic agent is the duration of the protective effect. After treatment, the cat will be protected from parasites for 21 days, and from fleas for about 1.5 months.

A spray is considered a popular and economical option. One bottle of Frontline is enough for a year of regular use. This drug is a frequent choice of cat breeders, as well as owners with more than one pet.

Instructions for use

Processing the animal takes no more than half an hour

. Before using it, it is recommended that you read the instructions for use included with each package. If drops are chosen for treatment, you must carefully cut off the tip of the plastic pipette. The fur between the cat's shoulder blades is parted with your hands, and the oily liquid is applied to the skin in a thin strip. The drug is quickly absorbed, no need to rub it in. It is forbidden to wash the cat 2 days before the procedure and for several days after it. Any moisture in your pet's fur is undesirable; it must be protected from rain or dew. If there are several cats living in the house, you will have to limit their contacts to avoid mutual licking. Children should not pet their pet for 3-4 days after treatment.

Vaccination schedule for kittens

Frontline Combo in the form of drops can be used to treat otodectosis. First, the auricle is thoroughly cleaned of brown crusts using cotton swabs and a special non-greasy lotion. Then 5-6 drops of the drug are carefully poured into the ear. The cat needs to be held tightly to prevent it from shaking its head.

The auricle is folded and gently massaged until the product is completely absorbed. In case of severe infection, the treatment is repeated after 4-5 days.

Frontline spray is suitable for treating kittens and smooth-haired cats. The procedure is best done outdoors. Before work, the cat's ears, eyes and nose are moistened with water, and the fur is combed with a brush or comb. The bottle is shaken and sprayed, kept at a distance of 15 cm from the animal. The product is evenly distributed throughout the body, including paws, tail, head, stomach

It is important to ensure that the drug does not get into the eyes and mouth of the animal. For 1 kg of cat's weight you will need 2-4 presses on the pump of a 250 ml bottle

There is no need to rub in the spray; the drug begins to act immediately after absorption. If necessary, the cat can be bathed the very next day after spraying with the spray. If several animals live in the house, simultaneous treatment must be carried out. It is recommended to spray the cat's bedding or her favorite chair with the product. This procedure is guaranteed to protect against ticks and prevent secondary infection.

Mode of application

Frontline flea control drops and spray are applied in different ways.

Procedure for applying Frontline Combo:

• break off the tip of the tube;
• push back the fur;
• Apply drops to the withers area.

On a note! Before the procedure, it is advisable not to wash the four-legged dog for 3 days.

Spot On Frontline drops are applied once to dry, intact skin. The tip of the tube is broken along the notch line, the fur is pulled apart in the area of ​​the shoulder blades and the medicine is applied in the dosage specified in the instructions.

Additional treatments are carried out no more than once every 4 weeks.

If there are several animals living in the house, it is necessary to treat each one in accordance with the instructions. Rugs are replaced or disinfected.

If your pet needs to be treated with Frontline spray, it is better to do it outside or in a well-ventilated area. If there are aquariums with fish, then they are covered first, and it is better to remove feathered pets from the room altogether.

Protect the animal from getting the drug inside by wearing a protective collar or muzzle. The bottle is shaken before use and kept in an upright position when applied. Spraying is carried out at a distance of 10-20 cm.

The entire body of the pet is treated with Frontline spray against hair growth, as well as the ears and chest. The medicine in the eye and nose area is applied manually, wearing gloves. 20-30 minutes after the procedure, the pet’s fur is combed. Until the fur is dry, it is prohibited for the animal to be near heating devices or open fire.