BI Frontline Combo drops for dogs to protect against ticks and fleas 20-40 kg, L pipette 2.68 ml

Properties

Frontline Combo refers to combined insectoacaricidal drugs with contact action.

Frontline Combo is active against:

• fleas (mature and preimaginal stages of development) Ctenocephalides spp.;
• lice eaters Felicola subrostratus, Trichodectes canis;
• ixodid ticks (all developmental phases) Dermacentor variabilis, Rhipicephalus sanguineus, Ixodes scapularis, Ixodes ricinus, Ixodes holocyclus, Haemaphysalis longicornis, Haemaphysalis flava, Haemaphysalis campanulata, Haemaphysalis leachi, Amblyomma americanum;
• mosquitoes Aedes aegypti;
• sarcoptoid mites Sarcoptes scabiei var. canis.

Recommendations when choosing a product

When choosing a suitable anti-tick product, you need to focus on the dog’s health, its weight, the presence of allergies to the components included in the composition and affordability.

Table: advantages of different Frontline tools

Among the Frontline products, you can easily choose the drug that is suitable for your four-legged friend. The main thing is to take into account the individual characteristics of the pet. Before using antiparasitic drugs, do not be lazy to consult with a veterinarian and carefully study the background information. The effectiveness and safety of products usually depends on strict adherence to instructions.

Dosage and method of administration

Frontline Combo is administered to animals once by applying drops to dry, intact skin using pipettes of various packaging.

Before treatment, break off the tip of the pipette, spread the animal’s fur in the back area (between the shoulder blades) and, pressing the pipette, apply the drug to the skin in the withers area at one or several points in a minimum dose of 0.067 ml/kg, according to the table:

To treat dogs weighing more than 60 kg, use a combination of pipettes of different volumes at a rate of 0.067 ml/kg. Do not wash or bathe animals with detergents, do not allow animals into natural bodies of water for 48 hours after treatment, and also apply the drug to wet or damaged skin. Repeated treatments of animals are carried out according to indications, but not more than once every 3 weeks.

Why choose Frontline products

Frontline medications are produced by Merial, which is the largest manufacturer of veterinary products for various purposes:

• antiparasitic agents against fleas, ticks and worms;
• vaccines and therapeutic preparations for cats, dogs, horses, pigs, birds.

Experience is more than 15 years. The share of the global veterinary products market is more than 15%. The range is designed in such a way that every dog ​​owner can find a solution to their pet’s problems in different situations.

Among the Frontline products there is one that is right for your dog

You can choose a product from the Frontline line even under the following conditions:

• the dog suffers from allergic reactions to most drugs;
• the dog is aggressive (it is difficult to get close and handle);
• the dog weighs little (less than 1 kg);
• this is a newborn puppy;
• the dog is constantly in contact with water (this reduces the effectiveness of many flea and tick protection products).

Trusted by pet owners all over the world. Since the existence of Frontline products, they have carried out over 1.5 billion treatments against ticks and fleas. This means that every second Frontline is applied to at least three pets!

Updated generation of insecticides

New generation drugs include Frontline Nexgard and Nexander Spectra. The first effectively fights blood-sucking parasites, and the second cleanses the body of helminths.

These two products are produced in the form of tablets, but not ordinary ones, but chewable ones, with a pleasant smell and taste.

Benefits of the insecticide:

• ideal for animals that require frequent bathing and shampooing;
• used for pets with skin diseases;
• can be mixed into food or given separately;
• thirty minutes is the time during which the tablet completely dissolves;
• as soon as the medicine takes effect, you can safely contact your pet and let him near other puppies and children;
• One dose of medication is enough to cleanse the dog’s body of parasites;

There are four dosage options for the drug:

• for animals weighing 2-4 kilograms, the dose is 11.3 milligrams;

• 4.1-10 kilograms – 28.3 milligrams;
• 10.1-25 kilograms – 68 milligrams;
• 25.1-50 kilograms – 136 milligrams.

If your pet's weight exceeds 50 kilograms, you can calculate the dose yourself: 2.5 milligrams per kilogram of weight.

The drug is contraindicated for puppies less than two months old or weighing less than 2 kilograms.

Frontline anti-tick tablets can be given to pregnant and lactating animals without restrictions.

Product line

The company presents a fairly wide range of products in various categories. Manufactured medications are classified by purpose, dosage and effect. As for flea products, the brand is represented by the following range of drugs:

• "Frontline Tri-Act";
• "Frontline NexGar" and "Nexander Spectrum";
• "Frontline Combo";
• "Frontline Spot On";
• Frontline Spray.

All these drugs effectively fight parasites and protect your pet from repeated infections.

special instructions

If there is increased individual sensitivity to the components of the drug and signs of allergic reactions appear, the treatment is stopped, the drug is washed off with water, and antihistamines are given orally. + When working with Frontline Combo, you should follow the rules of personal hygiene and safety precautions provided for working with medicinal products for animals. While working with the medicine, you are not allowed to drink, smoke, or eat. If Frontline Combo accidentally gets on the skin or mucous membranes, it should be washed off with a stream of water. After finishing work, wash your hands with warm water and soap. Empty drug pipettes must not be used for household purposes; they must be disposed of with household waste.

Release form:

Indications for use

All drugs in the Frontline series are prescribed to cure parasites and prevent their infection. So, they help from:

• fleas;
• lice eaters;
• ixodid ticks;
• scabies (sarcoptoid) mites – Spray, NexgarD and Spectra do not work against them;
• lice;
• mosquitoes

The Tri-Act form also has a repellent and insecticidal effect against dipterous insects: mosquitoes, burner flies, mosquitoes. And NexgarD Spectra destroys the larvae of heartworms and gastrointestinal nematodes: toxocara, hookworm, trichocephalosis.

Any medicine from Merial is indicated for:

• entomosis – diseases caused by insects;
• acaroses – pathologies that arose due to mites;
• otodectosis - ear scabies;
• allergic dermatitis caused by fleas (in complex therapy).

If, in addition to these conditions, there is a risk of contracting dirofilariasis, NexgarD Spectra is prescribed.

Efficiency

Frontline drops for dogs

Frontline drops for dogs reviews are mostly positive. This confirms the effectiveness of the product, as well as safety for your pet.

I started using Frontline drops after an allergic reaction occurred to other means of similar action. My dog’s body accepted this drug well. We've been using it for two years now. 2 treatments are enough for the season.

Marina, Moscow

An effective drug. The treatment procedure takes 5 minutes, the effect lasts 3 months. I have been buying this for my dog ​​for fleas for three years now. No allergic reaction was observed. Once it turned out that she licked it off the fur, a lot of saliva came out and that was all. A day later everything got better.

Angelina, St. Petersburg

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Triple action insecticide

Regardless of the breed of the animal, it can become infected with fleas, ticks and various types of flying insects. To destroy these parasites, you can use Frontline Three - Act. The insecticide has a quickly effective effect, and re-infection after treatment practically does not occur.

It can be used as a medicine for the prevention of:

• anaplasmosis;
• ehrlichiosis;
• leishmaniasis.

This drug has passed all kinds of tests. It is harmless to your pet. The product is completely safe, suitable for puppies starting from the second month of life. It is also suitable for pregnant and lactating animals.

The insecticide is available in five different packages, depending on the weight of the pet.

How to use:

• the animal's skin must be clean and undamaged;
• remove the pipette from the blister;
• put two points, one between the shoulder blades, the second on the back of the head;
• Before applying the Frontline insecticide, we part the fur, only after that we drip drops (with regards to puppies, the application procedure is similar for them).

In order not to harm your pet, it is recommended to do everything according to the instructions included.

Frontline spray

The aerosol product is produced in bottles of 100; 250 ml.

The cost of a 100 ml bottle in September 2022 is 845 rubles.

The spray protects cats from ixodid ticks for 3 weeks, fleas - 6 weeks. The dogs will be free of ectoparasites for 5 and 12 weeks respectively. Dispense the drug with the number of presses on the spray head in accordance with the table:

The table provides recommendations for treating pets with short hair. For long-haired dogs, the number of presses is doubled. To prevent a cat or dog from licking the insecticide, place a neck collar, muzzle, or tie the closed jaws with a rope while it dries. Avoid contact of the aerosol with the eyes. Problem areas are treated with your finger after wearing gloves.

The animal should not be allowed to get wet for two days after treatment. There are no restrictions on the weight and age of the animal. The aerosol is stored for 2 years at temperatures from 0 to 25 °C.

Drug safety studies

The instructions indicate that, according to GOST 12.1.007-76, medicines from the Spot On, Tri-Act, Combo and Spray lines belong to the 3rd hazard class (moderately hazardous substances), and NexgarD and Spectra - to the 4th class ( low-hazard substances). These results are confirmed by research from the manufacturer.

For the experiment, 4 primary groups were formed. The first was not treated with medication, the second received the drug in a single dosage, the third in a three-fold dosage, and the fourth in a five-fold dosage. The condition of the animals was monitored using clinical tests, skin biopsy, and histological studies.

The results of the analyzes showed that there were no differences in the well-being and condition of the pets of different control groups.

Additionally, a similar analysis was carried out on puppies. It was found that in some kittens, the antiparasitic agent leads to increased discharge from the eyes and the formation of dandruff. But in general, children tolerate the medication well.

Today, the results of pharmacological research continue. Over the entire period of the program, Frontline has treated over 3 million animals of different ages, sizes and breeds. Only isolated cases of treatment regarding side effects were recorded. However, all of them were not directly related to the use of the drug - it could only influence the occurrence of negative reactions indirectly.

However, a number of breeders claim that the medication has a mutagenic effect. In particular, there have been cases of puppies being born with conjunctivitis and dermoids of the eyelids from parents who previously gave birth to healthy litters. These data have not been clinically confirmed, but they should be taken into account by nursery owners.

Precautionary measures

As mentioned above, the medication is one of the drugs that is low-risk for the body of dogs.
Complies with GOST standard 12.1.007.76 However, when working with Frontline, as with any medicine, precautions should be taken:

Strictly observe the dosage of the drug. Do not use in conjunction with an anti-parasitic collar. Observe age restrictions on the use of the product. Use with caution on weakened and older dogs. Use with caution for pregnant and lactating individuals. If possible, during these periods, avoid any chemical exposure without special indications. Be sure to check with your veterinarian about possible interactions between fipronil and other medications. Before use, you should make sure that the dog does not have an individual intolerance to the components of Frontline.

Contraindications

The drug Frontline is not toxic to cats, so the list of contraindications for using the drug consists of only two points:

• Individual intolerance to the drug in animals;
• The age of the kitten is 1 day after birth.

Possible side effects:

Hypersalivation.

Important!

If side effects occur, you should immediately stop using Frontline and wash it off your pet's fur. In case of severe allergic reactions, it is necessary to consult a veterinary doctor for help and administer anti-allergy drugs.

In addition, when choosing a particular product, it is important to pay attention to what age or weight of the animal it is intended for. The product range of this manufacturer allows you to select suitable drugs for both adults and kittens. This is especially convenient for those owners who have not one cat, but several pets of different ages.

This is especially convenient for those owners who have not one cat, but several pets of different ages.

In the range of the series you can find:

By the way, Frontline drops and sprays intended for cats can also be used for ferrets, which are increasingly found as pets. What are the specific features of certain Frontline tools?

Types of drugs and principle of action

The manufacturer produces the following types of Frontline drugs:

1. Combo for dogs.
2. Combo for ferrets and cats.
3. Spot-on.
4. Spray.
5. Tri-ACT.

The list of active ingredients and their concentration in the preparations is shown in the table:

Fipronil and Permethrin interrupt the transmission of nerve signals to the muscles of arthropods, immobilizing them. Methoprene is structurally reminiscent of an arthropod hormone that is involved in the synthesis of chitin. In immature forms, the maturation process stops. The larval stages may not survive to the age where they can reproduce.

Frontline components do not enter the bloodstream, accumulate in the sebaceous glands, hair follicles, epidermis, hairs and provide long-term protection against parasites.

Processing technique

When applying drops, it is recommended to wear rubber gloves. You cannot bathe your pet for two days before treatment and for the same amount of time after it. Drops should not be used if the animal has an infectious disease and is weakened. The next day after treatment, you should not pet the animal or allow it near children. You should not eat, smoke or drink during surgery. Healthy pets also need to be treated.

The drugs are not used if there are injuries on the skin or if the fur or skin is damp. Apply to dry and clean skin. We do not combine drops with other insectoacaricidal agents. Do not use drops if you yourself suffer from allergies, respiratory or dermatological diseases. We apply it like this:

1. Before applying, remove the dog's collar, accessories, and clothing;
2. We spread the fur at the withers (where the dog cannot lick it);
3. We drip onto the skin. We don't rub it in. Do not touch until the wool is dry.

When applying the spray, you also need to follow the rules. We put a muzzle on the pet, a neck collar, and fix the jaws. Do not remove until the wool is dry. Apply to dry skin and coat. We put on gloves.

We spray anti-hair spray all over the dog's body. If the hair is long, lift it. We cover the dog's eyes when treating the ears and chest. Lightly rub the spray into the areas around the eyes and nose with your fingertips. If the spray causes vomiting, muscle tremors and salivation in the animal, rinse with plenty of water. We also treat the bedding with a spray. We do not allow the dog near the fire for an hour after the procedure.